diff --git a/src/human_number.rs b/src/human_number.rs
new file mode 100644
index 0000000..61c81bd
--- /dev/null
+++ b/src/human_number.rs
@@ -0,0 +1,148 @@
+use std::convert::TryInto;
+use std::fmt;
+
+use serde::de::{Deserializer, Error, Unexpected, Visitor};
+
+pub fn deserialize<'de, D>(deserializer: D) -> Result<Option<u64>, D::Error>
+where
+    D: Deserializer<'de>,
+{
+    deserializer.deserialize_any(HumanNumberVisitor)
+}
+
+struct HumanNumberVisitor;
+
+impl<'de> Visitor<'de> for HumanNumberVisitor {
+    type Value = Option<u64>;
+
+    fn expecting(&self, formatter: &mut fmt::Formatter<'_>) -> fmt::Result {
+        formatter.write_str("unsigned number or quoted human-readable unsigned number")
+    }
+
+    fn visit_i64<E>(self, v: i64) -> Result<Self::Value, E>
+    where
+        E: Error,
+    {
+        v.try_into()
+            .map_err(Error::custom)
+            .and_then(|v| self.visit_u64(v))
+    }
+
+    fn visit_u64<E>(self, v: u64) -> Result<Self::Value, E>
+    where
+        E: Error,
+    {
+        Ok(Some(v))
+    }
+
+    fn visit_str<E>(self, v: &str) -> Result<Self::Value, E>
+    where
+        E: Error,
+    {
+        let v = v.trim();
+
+        if v.is_empty() {
+            return Err(Error::invalid_value(
+                Unexpected::Str(v),
+                &"non-empty string",
+            ));
+        }
+
+        // Using `bytes` instead of `chars` here because `split_at` takes a byte offset
+        match v
+            .bytes()
+            .map(|byte| byte as char)
+            .position(|ch| !(ch.is_numeric() || ch == '.'))
+        {
+            Some(unit_index) => {
+                let (value, unit) = v.split_at(unit_index);
+                let value: f64 = value.parse().map_err(Error::custom)?;
+
+                let multiple: u64 = match unit.trim_start() {
+                    "KB" | "kB" => 1000,
+                    "MB" => 1000 * 1000,
+                    "GB" => 1000 * 1000 * 1000,
+                    "TB" => 1000 * 1000 * 1000 * 1000,
+
+                    "KiB" => 1024,
+                    "MiB" => 1024 * 1024,
+                    "GiB" => 1024 * 1024 * 1024,
+                    "TiB" => 1024 * 1024 * 1024 * 1024,
+
+                    unit => {
+                        return Err(Error::invalid_value(
+                            Unexpected::Str(unit),
+                            &"known unit of measurement",
+                        ))
+                    }
+                };
+                let value = value * (multiple as f64);
+
+                Ok(Some(value.round() as u64))
+            }
+            None => {
+                // No unit found, interpret as raw number
+                v.parse().map(Some).map_err(Error::custom)
+            }
+        }
+    }
+
+    fn visit_none<E>(self) -> Result<Self::Value, E>
+    where
+        E: Error,
+    {
+        Ok(None)
+    }
+
+    fn visit_some<D>(self, deserializer: D) -> Result<Self::Value, D::Error>
+    where
+        D: Deserializer<'de>,
+    {
+        deserializer.deserialize_any(self)
+    }
+}
+
+#[cfg(test)]
+mod test {
+    use serde::de::value::Error;
+    use serde::de::IntoDeserializer;
+
+    use super::deserialize;
+
+    #[test]
+    fn test_deserialize() {
+        fn check_result(input: &str, value: u64) {
+            assert_eq!(
+                deserialize(input.into_deserializer()),
+                Ok::<_, Error>(Some(value))
+            );
+        }
+
+        check_result("1234", 1234);
+        check_result("1234 ", 1234);
+        check_result(" 1234", 1234);
+        check_result(" 1234 ", 1234);
+
+        check_result("1234kB", 1234 * 1000);
+        check_result("1234KB", 1234 * 1000);
+        check_result("1234MB", 1234 * 1000 * 1000);
+        check_result("1234GB", 1234 * 1000 * 1000 * 1000);
+        check_result("1234TB", 1234 * 1000 * 1000 * 1000 * 1000);
+
+        check_result("1234KiB", 1234 * 1024);
+        check_result("1234MiB", 1234 * 1024 * 1024);
+        check_result("1234GiB", 1234 * 1024 * 1024 * 1024);
+        check_result("1234TiB", 1234 * 1024 * 1024 * 1024 * 1024);
+
+        check_result("1234 kB", 1234 * 1000);
+        check_result("1234 KB", 1234 * 1000);
+        check_result("1234 MB", 1234 * 1000 * 1000);
+        check_result("1234 GB", 1234 * 1000 * 1000 * 1000);
+        check_result("1234 TB", 1234 * 1000 * 1000 * 1000 * 1000);
+
+        check_result("1234 KiB", 1234 * 1024);
+        check_result("1234 MiB", 1234 * 1024 * 1024);
+        check_result("1234 GiB", 1234 * 1024 * 1024 * 1024);
+        check_result("1234 TiB", 1234 * 1024 * 1024 * 1024 * 1024);
+    }
+}
diff --git a/src/lib.rs b/src/lib.rs
index 59c26d7..e606509 100644
--- a/src/lib.rs
+++ b/src/lib.rs
@@ -26,6 +26,7 @@ use serde::Deserialize;
 mod config;
 mod dump;
 mod format;
+mod human_number;
 mod log;
 
 use crate::config::Config;
@@ -195,8 +196,11 @@ struct VgpuProfileOverride<'a> {
     multi_vgpu_supported: Option<u32>,
     pci_id: Option<u64>,
     pci_device_id: Option<u64>,
+    #[serde(with = "human_number")]
     framebuffer: Option<u64>,
+    #[serde(with = "human_number")]
     mappable_video_size: Option<u64>,
+    #[serde(with = "human_number")]
     framebuffer_reservation: Option<u64>,
     encoder_capacity: Option<u64>,
     bar1_length: Option<u64>,